Biden also urged young people in their 20s and 30s in particular to get inoculated.
The president, who has made fighting the coronavirus a key priority of his administration, had previously announced July 4 as a target date for when Americans can gather in small groups to signal a return to greater normalcy in the middle of the pandemic.
Biden's new goal comes as the administration faces increasing, though not unexpected, challenges of getting shots into the arms of people who are hesitant about the vaccine. The new target takes that reality into account.
Biden's new goal includes having 160 million adults fully vaccinated by the Fourth of July.