The royal has made several sensational claims in his autobiography, Spare, and has opened up about his private life, sharing that he lost his virginity to an older woman in a field behind a pub.
He also shared that he was circumcised and told how he suffered a frostbitten penis after a North Pole expedition.
Royal expert Russell Myers went on Kelly's programme to discuss what Harry had revealed - but the chat left Kelly cringing.
As Myers mentioned the circumcision and frostbite stories, the TV star looked horrified, saying: "I don't need to know that!
"Don't need to know about Prince Harry's willy," she added.
Myers then moved on to talk about Harry opening up about losing his virginity, which the royal reportedly says was "a humiliating episode" that was with "an older woman who liked macho horses and who treated me like a young stallion".
But Kelly looked utterly shocked by the whole thing.
"Stop it, stop it, I can't handle it!" she said, covering her mouth as she giggled.
"My toes may never uncurl again!" added the TV star.
"This has got to stop," she said ahead of the release of episodes of the programme.
"Once this comes out on Thursday, once the book has come out…. they can’t just keep talking about their families," she went on.